The AIDS was the most serious form resulting from the infection HIV. the HIV was retrovirus that usually attacks the vital organ the system of human immunity like the cell of T CD4+ (a kind of T cell), makrofag, and the cell dendritik. The HIV directly and indirectly damaged the cell of T CD4+, in fact the cell of T CD4+ was needed so that the system of body immunity functions good.Without therapy antiretroviral, the length median of the development of the HIV infection became the AIDS was nine to ten years, and the time median lived after experiencing the AIDS only around 9.2 months. Nevertheless, the rate of the clinical development of this illness was very varying interpersonal, from two weeks to 20 years. Many factors that influenced the rate of this development. The available factor including the strength of the body to remain against the HIV like the function of immunity of the body of the person's public that was infected.
The older person had the weaker immunity system, so as to be risky higher experienced the development of the illness that was fast than the younger person. Access that not all that towards the maintenance of the health and the existence of the other infection like tuberculosis also could speed up the development of this illness. The person's Genetics that was infected played the important role. Several people were immune to several grooves of HIV. Contohnya was the person with the mutation of CCR5-Δ32 (delesi 32 nukleotida to the gene penyandi the receptor chemokine CCR5 that influenced the function of the T cell) that was immune to several HIV. Grooves the HIV varied genetically and had various grooves or the different form and caused the rate of the development of the different clinical illness. The Use of therapy antiretroviral that was very active could extend both the median of the AIDS and the time median of development time remained.
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